Biological Responses To Dna Damage; Manufacturer: Cold Spring Harbor Laboratory Press; Paperback

Manufacturer: Cold Spring Harbor Laboratory Press
Series#:LXV; Cold Spring Harbor Symposia on Quantitative Biology (Paperback); Paperback; Illustrations, Colour Plates, Indexes
613 pages
Published: May 2001
Cold Spring Harbor Laboratory Press
ISBN: 0879696060

Living cells have evolved many ways of coping with metabolic events and environmental influences that damage DNA. These mechanisms, and the frequent progression to cancer that results when they go awry, are reviewed in this volume by authors from over sixty of the world's leading laboratories. The topics discussed include DNA repair, mutagenesis and other damage-tolerance functions, checkpoint control, apoptosis, and adaptation. They draw from studies on human and yeast cells. Current, but with a valuable historical perspective, this volume has the depth and lasting value typical ofthis most prestigious series and is essential reading for investigators of DNA replication, cell cycle control, and tumorigenesis.Living cells have evolved many ways of coping with metabolic events and environmental influences that damage DNA. These mechanisms, and the frequent progression to cancer that results when they go awry, are reviewed in this volume by authors from over 60 of the world's leading laboratories.